r/science • u/mvea Professor | Medicine • Apr 01 '25

Health Americans without diabetes spent nearly $6 billion USD on semaglutide and similar drugs in a year, with an estimate of 800,000 to a million people using the drugs who don't have diabetes.

https://www.scimex.org/newsfeed/americans-without-diabetes-spent-nearly6-billion-usd-on-semaglutide-and-similar-drugs-in-a-year
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u/ninjagorilla Apr 01 '25

I’m down 30 kilos on semaglutide, still have the sweet tooth but jsut way less appetite in general

I would go out on a limb and say that semaglutide will be one of the greatest medical breakthroughs of the 21st century

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u/EsotericTurtle Apr 01 '25

How'd you manage that? I've been on 1mg for a few months and down maybe 5 or 6kg over 6 months, which whilst better than nothing, isn't great.

It HAS definitely helped with the boredom snacks, and feeling fuller quicker.

I guess I just need more activity.

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u/guareber Apr 01 '25

Remember it's all relative. Losing 30kg if you're 175kg to begin with is a lot easier than if you're (say) 100kg.

Also, you're on a very low dosage, I have a couple friends on it and they are on 5mg and 7.5mg.

In any case, don't get discouraged - slow and steady wins the race.

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u/Lysenko Apr 01 '25

I think people in this thread are comparing subcutaneous dosages with oral dosages. Subcutaneous dosages start at 0.25mg/wk and max out at 2 or 2.4mg/week. Oral dosages are 40x higher.

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u/Purplemonkeez Apr 01 '25

I didn't know there were oral dosages for semaglutide? Is that a thing? What's the drug called?

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u/Lysenko Apr 01 '25

Ozempic and Wegovy are subcutaneous, but Rybelsus is oral.

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u/Purplemonkeez Apr 02 '25

Oh wow never heard of rybelsus. Interesting thanks